Exploring Innovation of Hyaluronic Acid Powder in Oral Care Formulations

Hyaluronic acid (HA), as a natural biopolymer, possesses excellent water-retaining capacity, lubricating properties and permeation-regulating functions. It aids in maintaining tissue environment stability and supports healthy cellular metabolism. With ongoing application research, hyaluronic acid is demonstrating broad application prospects in the field of oral health and care.

Within oral care products, hyaluronic acid leverages its outstanding biocompatibility and unique physicochemical properties to serve as a premium ingredient across diverse categories including toothpaste, mouthwash, oral gels, and mucosal care solutions. It enhances product mildness, moisturising sensation, and overall user experience.

Green Spring Technology is dedicated to supplying high-purity, multi-molecular-weight cosmetic-grade hyaluronic acid powder for the oral care sector. Our products boast exceptional stability and compatibility, meeting diverse development requirements for oral care formulations. This empowers brands to create safer, more comfortable, and functionally advanced oral health innovations.

1. Application Potential of Hyaluronic Acid Powder in Oral Health Care

As a natural polysaccharide, hyaluronic acid powder possesses excellent biocompatibility and mild physicochemical properties, making its application in oral care products increasingly noteworthy. It demonstrates significant potential in maintaining oral soft tissue health and improving the oral environment.

1.1 Complementing Daily Care, Enhancing the Health Experience

Research indicates hyaluronic acid can be incorporated into daily oral care routines to support gum health maintenance. Integrating hyaluronic acid-containing products with regular oral hygiene practices enhances the care experience and promotes overall oral environmental health [7]. From a tissue compatibility perspective, hyaluronic acid acts gently within the oral environment, making it suitable for daily care formulations.

1.2 Premium Ingredients Empowering Oral Care Innovation

Owing to its unique molecular structure and physicochemical properties, hyaluronic acid powder serves as a superior functional ingredient in toothpastes, mouthwashes, and oral gels, enhancing product usability and comfort. Green Spring Technology supplies high-purity cosmetic-grade hyaluronic acid raw materials, offering excellent stability and compatibility. These meet diverse development needs for oral care products, enabling brands to create gentler, more effective oral health solutions.

2 Innovative Applications of Hyaluronic Acid in Oral Care

As a bioactive component naturally present in periodontal connective tissue, hyaluronic acid powder possesses excellent biocompatibility and unique physicochemical properties. Its application in premium oral care products has garnered significant attention in recent years . Its superior moisturising properties, film-forming capabilities, and tissue affinity offer new avenues for innovative oral health product development.

Research indicates hyaluronic acid powder can serve as an adjunct ingredient in daily oral hygiene routines. When incorporated into conventional oral cleansing, products containing hyaluronic acid enhance the care experience and promote overall oral health. Xu Yi et al. [9] demonstrated that combining hyaluronic acid with professional cleaning methods delivers a more comfortable oral experience.

As a natural component of the extracellular matrix, hyaluronic acid regulates local hydration and maintains tissue moisture. High-molecular-weight hyaluronic acid also forms protective films, contributing to a healthier oral environment. Multiple studies indicate that incorporating hyaluronic acid into oral care routines delivers a more comprehensive care experience.

Green Spring Technology specialises in supplying dental-grade hyaluronic acid powders. Our products feature high purity, multiple molecular weight options, and excellent compatibility, enabling broad application in toothpaste, mouthwash, oral gels, and other formulations. This empowers brand clients to develop more competitive and innovative oral care solutions.

3. Application Potential of Hyaluronic Acid in Implant Care

As a natural biopolymer, hyaluronic acid demonstrates broad application prospects in premium oral care—particularly peri-implant care—due to its exceptional biocompatibility and unique physicochemical properties. Its outstanding moisturising and film-forming capabilities provide a gentle care environment for the peri-implant region.

Research indicates that incorporating hyaluronic acid-containing products into routine oral hygiene enhances the overall care experience. Zhang Li et al.'s [11] study demonstrated that adding hyaluronic acid components yields positive care outcomes for the peri-implant region. Compared to mechanical cleaning alone, products incorporating hyaluronic acid exhibit superior comprehensive advantages in improving the local environment.

Within professional oral care, researchers have explored combining hyaluronic acid powder with other care ingredients. Experiments indicate that hyaluronic acid-based care regimens offer users a more comfortable experience, delivering comparable efficacy to certain traditional care ingredients while being gentler.

4 Applications and Prospects of Hyaluronic Acid in Post-Oral Surgical Care

Hyaluronic acid powder demonstrates significant application potential in post-oral surgical care due to its excellent biocompatibility and moisturising properties. Research indicates it provides positive microenvironmental support during post-extraction care, promoting orderly tissue recovery.

Experiments demonstrate that application of high molecular weight hyaluronic acid gel results in more orderly local tissue arrangement, suggesting it may create favourable conditions for wound healing. Further studies confirm that hyaluronic acid can regulate the local microenvironment to provide nutritional support for tissues, aiding the healthy recovery process.

Green Spring Technology supplies dental-grade hyaluronic acid powders characterised by high purity, multiple molecular weight options, and excellent stability. These are suitable for developing products such as oral gels and post-operative care solutions, providing reliable support for brand clients innovating premium oral care offerings.

5 Applications of Hyaluronic Acid in Implant Care

Hyaluronic acid powder demonstrates application potential in post-operative care for dental implants due to its superior moisturising and film-forming properties. Its excellent biocompatibility aids in creating a suitable microenvironment, offering innovative directions for post-operative care products.

Research indicates that hyaluronic acid products can support wound condition maintenance in the early post-operative phase. By forming a protective film, they maintain a moist environment and enhance comfort. Although study results vary due to factors such as evaluation methods, its value as a functional raw material remains noteworthy.

6 Innovative Applications of Hyaluronic Acid Powder in Oral Mucosal Care

Hyaluronic acid powder, with its exceptional moisturising and film-forming properties, has become a key functional ingredient in oral mucosal care products. Its excellent biocompatibility delivers a gentle yet effective care experience for the oral cavity.

Research indicates that oral care products containing hyaluronic acid powder significantly enhance user comfort. Experiments demonstrate that after using products with 0.2% hyaluronic acid, users' oral conditions show marked improvement. Hyaluronic acid forms a breathable protective film on mucosal surfaces, effectively shielding against external irritants while maintaining localised moisture.

Green Spring Technology leverages advanced bio-extraction and molecular modification techniques to develop a series of hyaluronic acid powder solutions specifically for oral care. Our products utilise precise molecular weight control technology to fulfil diverse functional requirements—from low molecular weight rapid penetration to high molecular weight long-lasting film-forming properties—offering formulators flexible and versatile options.

This hyaluronic acid powder exhibits exceptional sensory properties, significantly enhancing the smoothness and skin-adherence of end products. It demonstrates excellent formulation compatibility and system stability, suitable for diverse formulations including mouthwashes, oral gels, and mucosal care solutions. All products adhere to internationally recognised quality control standards, undergoing rigorous quality testing and safety assessments to ensure batch-to-batch consistency and regulatory compliance.

Please contact us at helen@greenspringbio.com or WhatsApp: +86 13649243917 for product specifications and quotations. Green Spring Technology provides specialised, bespoke raw material solutions to advance the technological evolution and market innovation of oral care products.

References

[1] Huang Sili, Guo Xueping, Yang Guilan, et al. Recent Advances in the Application of Hyaluronic Acid [J]. Food and Medicine, 2009, 11(1): 50-53.

[2] Long  X,  Chen  G,  Cheng AH,  et  al. A randomized  con- trolled  trial  of  superior  and  inferior  temporomandibular joint  space  injection  with hyaluronic acid in treatment of anterior  disc  displacement  without  reduction [J].  J   Oral Maxillofac  Surg,  2009,  67（2）：357-361.

[3] Escoda-Francolí J,  Vzquez-Delgado  E,  Gay-Escoda  C.Scientific evidence on the usefulness of intraarticular hyaluronic acid injection in the management of temporo- mandibular  dysfunction[J].  Med  Oral  Patol  Oral  Cir  Bucal, 2010,  15（4）：e644-e648.

[4] Li Chunjie, Zhang Yifan, Jia Yuanyuan, et al. A systematic review of a clinical randomised controlled trial on the treatment of temporomandibular joint dysfunction with sodium hyaluronate [J]. West China Journal of Stomatology, 2011, 29(5): 488-493.

[5] Liu Peicai, Wang Dong, Peng Cheng, et al. Effects of sodium hyaluronate on matrix metalloproteinases 2 and 3 in synovial fluid of patients with temporomandibular joint osteoarthritis [J]. Chinese Journal of Stomatological Research: Electronic Edition, 2011, 5(4): 356-360.

[6] Zhao Jigang, Peng Guoguang, Liang Jingzhang, et al. Clinical study on the prevention of postoperative complications of condylar fracture by joint lavage and sodium hyaluronate injection [J]. Journal of Modern Stomatology, 2011, 25(2): 105-107.

[7] Wu Yafei, Huang Jiao, Xu Yi, et al. The role of Gengigel gel in the treatment of plaque-induced gingivitis [J]. Journal of Practical Stomatology, 2005, 21(4): 540-542.

[8] Sukumar S, Drízhal I. Hyaluronic acid and periodontitis [J]. Acta Medica (Hradec Kralove), 2007, 50(4): 225-228.

[9] Xu Yi, Frentzen M, JervΦe-Storm P-M. The role of hyaluronic acid in the treatment of chronic periodontitis [J]. West China Journal of Stomatology, 2004, 22(1): 32-34.