Magnesium Glycinate Powder 99%

Magnesium Bisglycinate 10% Powder

CAS No.: 14783-68-7

Assay (Elemental Mg): ≥ 10.0% on anhydrous basis

Free Amino Acid: ≤ 1.0% free glycine 

Testing Method: HPLC / ICP-OES

Appearance: White to off-white, free-flowing crystalline powder

Mesh Size: 100% through 80 Mesh

Bulk Density: 0.35 g/mL - 0.45 g/mL

Tapped Density: 0.50 g/mL - 0.65 g/mL

Certificates: BRCGS, IFS, Halal, Kosher

Sample: 10-50g Free Sample Available for R&D

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  • Description
  • Data Sheet

  • What is Magnesium Bisglycinate 10% Powder?


    Magnesium Bisglycinate 10% Powder is a standardized, free-flowing organic amino acid chelate raw material designed for structural dietary supplements. The core molecular identity consists of a central magnesium ion synthetically bonded to two molecules of glycine with the chemical formula Mg(C2H4NO2)2. Processed via fully reacted aqueous synthesis and automated spray drying, the ingredient provides a minimum 10.0% elemental magnesium content on an anhydrous basis (CAS No. 14783-68-7, Molecular Weight: 172.44 g/mol).

    Unlike conventional inorganic salts, this material is 100% pure and unbuffered, containing zero added magnesium oxide or magnesium carbonate. The complete heterocyclic ring structure shields the mineral core from premature dissociation in gastric acid, utilizing active transport via PepT1 peptide absorption pathways. This molecular preservation prevents unreacted ion release and localized osmotic shifts, eliminating gastrointestinal distress and laxative side effects during metabolic assimilation.

    For contract manufacturers (CMOs), the material optimizes plant-floor processing through rapid dissolution dynamics, dispersing completely at 15°C within 60 seconds. The neutral, low-odor profile prevents the abrasive, metallic mouthfeel common in unreacted mineral salts, making it ideal for ready-to-mix (RTM) powders and functional beverages. This structural stability guarantees strict batch-to-batch uniformity with zero pipeline sedimentation on high-speed industrial blending lines.


    Specification   

    Product Name

    Magnesium Bisglycinate Powder

    Chemical FormulaMg(C2H4NO2)2 

    CAS No.

    14783-68-7

    Molecular Weight172.44 g/mol, anhydrous molecular mass calculation

    Assay (Elemental Mg)

    ≥ 10.0% on anhydrous basis verified via HPLC / ICP-OES

    Free Amino Acid≤ 1.0% free glycine confirming 100% complete chelation

    Appearance

    White to off-white, free-flowing crystalline powder

    Odor & TasteCharacteristic, neutral, low-odor formulation base
    Mesh Size100% through 80 Mesh (≤ 180 μm) evaluating particle curve
    Loose Bulk Density0.35 g/mL - 0.45 g/mL monitored under USP <616> Method I
    Tapped Bulk Density0.50 g/mL - 0.65 g/mL ensuring optimal Hausner Ratio ≤ 1.30
    Cold Water DispersionCompletely disperses at 15°C within 60 seconds with zero ringing
    Loss on Drying≤ 5.0% evaluated under USP <731> constant weight at 105°C
    Ash Content≤ 5.0% determined via USP <561> inorganic residue analysis
    pH (1% Solution)7.5 - 8.5 establishing optimal potentio-metric aqueous stability
    Heavy MetalsPb ≤ 0.5 ppm; As ≤ 0.5 ppm; Cd ≤ 0.2 ppm; Hg ≤ 0.1 ppm (USP <232>/<233>)
    MicrobiologyTAMC ≤ 1,000 cfu/g; TYMC ≤ 100 cfu/g; E. coli & Salmonella: Negative (USP <61>/<62>)
    Regulatory StatusUSP Compliant; EP Certified; California Proposition 65 Compliant

     

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    Quality & Compliance


    Global Safety Registrations: Green Spring Technology automated manufacturing facilities strictly align with global food safety regulations under active, verified auditing certification under BRCGS (Grade A), IFS Food (Higher Level), US FDA Facility Registration, ISO 9001, and ISO 22000 standard networks.

    Dietary & Identity Compliance: The ingredient is fully cleared under Kosher, Halal, COSMOS, EU Organic, and USDA Organic regulatory frameworks, ensuring cross-national dietary supplement and food compliance audits.

    Heavy Metal Safeguards: Analytical batch release metrics strictly enforce Pb ≤ 0.5 ppm, As ≤ 0.5 ppm, Cd ≤ 0.2 ppm, and Hg ≤ 0.1 ppm, exceeding USP <232>/<233> and California Proposition 65 criteria.

    Contaminant & Residue Controls: Continuous screening ensures absolute compliance with Regulation (EC) No 396/2005 for pesticide residue limits and Regulation (EU) 2023/915 for environmental contaminants, maintaining a strictly Non-GMO, Non-Irradiation, and ETO-Free identity.

    Technical Regulatory Identification: Backed by a verified Statement of Non-Use of Organic Solvents, confirming a 100% pure water-based synthesis process with zero chemical solvent contamination, simplifying clean-label auditing for international functional nutrition brands.


    green-spring-technology-brcgs-ifs-halal-kosher-usda-organic-cosmos-certifications

    Key Advantages


    Aqueous Phase and pH Stability: The heterocyclic ring ensures thermodynamic stability across pH 3.5 - 8.5, preventing premature magnesium dissociation. The chelated matrix shields against organic acids and polyphenols, eliminating precipitation, solution turbidity, or discoloration in acidic liquid systems.

    Mechanical and Thermal Tolerance: The fully reacted crystalline bond resists extreme manufacturing stresses, maintaining homogeneity under high-shear emulsification, industrial homogenization, and pasteurization. The molecular encapsulation ensures zero metallic aftertaste or phase separation in liquid filling lines.

    Anti-Caking and Fluid Dynamics: The controlled bulk density profile yields an optimized Hausner ratio under 1.30, enhancing powder flowability. This specific grain structure resists moisture absorption and static agglomeration, eliminating hopper bridging and equipment wall adhesion.

    High Excipient Compatibility: The inert glycine envelope prevents chemical interaction, ensuring excellent compatibility with active vitamins and botanical extracts. It eliminates ascorbic acid oxidation and prevents the cross-linking degradation of gelatin or HPMC capsule shells.


    Applications


    • Solid Dosage Encapsulation (Two-Piece Hard Capsules): The powder particle profile (100% through 80 mesh) maps perfectly to high-speed rotary capsule filling equipment. The uniform mass flow rate minimizes capsule weight variations, while the optimized tapped density (0.50 - 0.65 g/mL) ensures exceptional filling uniformity for targeted lower-dose synergistic mineral complexes or multi-nutrient blends within standard HPMC or gelatin shells.

    • Ready-to-Mix (RTM) Sports Nutrition and Drink Packets: Due to rapid cold water dispersion kinetics (complete dissolution at 15°C within 60 seconds), the ingredient serves as a primary magnesium source in instantized stick packs. The low-odor, chemically neutral glycine shield guarantees zero abrasive mouthfeel, ensuring visual clarity and sediment-free reconstitution in consumer drink matrices.

    • Advanced Tablet Compression (Direct Compression Blends): The unique crystalline grain geometry yields excellent compressibility indices under mechanical pressure, preventing tablet capping, lamination, and tool surface fouling. It maintains robust structural hardness at lower compression forces while guaranteeing a rapid, predictable tablet disintegration profile compliant with USP <701> standards.

    • Fortified Liquid Oral Systems and RTD Beverages: Operating smoothly within pH 3.5 - 8.5 processing zones, the stable heterocyclic ring structure resists degradation during HTST pasteurization loops. This thermodynamic resilience prevents active mineral-protein cross-linking, entirely eliminating phase separation, product cloudiness, or heavy metallic aftertaste on high-throughput industrial beverage filling lines.


    magnesium-bisglycinate-10-powder-application-dosage-forms

    Technical FAQ


    Q1: How is the structural integrity of full reaction in Magnesium Bisglycinate 10% Powder differentiated from simple physical dry-blends during quality assurance auditing?
    A1: Complete molecular chelation is verified using Fourier Transform Infrared Spectroscopy (FTIR) to monitor the characteristic shift of the carboxylic acid carbonyl stretching vibration from 1590 cm-1 to the metal-coordinated ligand peak at 1640 cm-1. X-ray Powder Diffraction (XRD) further confirms the total disappearance of unreacted crystalline magnesium oxide reflections, ensuring a free glycine threshold of under 1.0% to validate a 100% fully reacted compound.


    Q2: What industrial process control protocol prevents the thermodynamic degradation and moisture-induced agglomeration of unbuffered Magnesium Bisglycinate Chelate complex during high-speed blending?
    A2: Advanced production lines utilize an automated low-temperature spray drying isolation loop to lock the micro-crystalline matrix before moisture absorption occurs. The moisture limit is strictly managed through real-time Karl Fischer titration monitoring, enforcing a strict loss on drying ceiling of under 5.0% to suppress hygroscopic powder bridging and prevent die-sticking on high-throughput rotary tablet presses.


    Q3: How does the manufacturer guarantee chemical homogeneity and zero structural separation of standardized Magnesium Amino Acid Chelate 10% Mg matrix when processed in continuous liquid oral dosage lines?
    A3: Homogeneity is locked during the aqueous phase reaction by maintaining specialized pH-controlled reaction vessels stabilized at a 7.5 - 8.5 range to prevent premature ligand-metal dissociation. Batch consistency is validated using Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES), ensuring that the elemental magnesium density remains strictly bounded between 10.2% and 11.5% with zero precipitation or ringing.


    B2B Sourcing & Supply Capabilities


    • Manufacturing Infrastructure: Green Spring Technology delivers mineral chelate manufacturing expertise established in 2000. Supported by an independent R&D laboratory for batch validation, the industrial plant maintains an annual output of 1,800 Metric Tons for standardized amino acid chelates.

    • Fulfillment Matrix and MOQ: The standard packaging configuration is 25 kg fiber drums lined with double-layered sterile polyethylene bags. To support clinical trials and formula profiling, Green Spring Technology provides a flexible factory-level minimum order quantity (MOQ) of 1 kg.

    • Global Logistics and Warehousing: Continuous international supply chain execution is anchored by a dedicated European warehouse in Paris, France. This infrastructure guarantees rapid ex-factory dispatch, optimal safety stock mitigation, and shortened transit timelines for multi-site contract manufacturers.

    • Customs Compliance and Sample Policy: Compliance protocols provide comprehensive documentation to accelerate cross-border customs clearance and eliminate supply chain risk. Evaluation and pilot-testing samples of 10 to 50 grams are available free of charge for corporate R&D divisions.

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