Rosemary Extract Ursolic Acid 98%

What is Rosemary Extract Ursolic Acid?

Ursolic acid is a triterpenoid compound present in natural plants, which has a variety of biological effects such as sedative, anti-inflammatory, antimicrobial, anti-diabetic, anti-ulcer, blood glucose lowering, etc. Ursolic acid also has obvious antioxidant function, in addition, ursolic acid can show its anticancer activity by inducing apoptosis, inhibiting cell cycle progression, inhibiting cell proliferation, inhibiting metastasis, and decreasing tumorigenesis through a variety of signaling pathways.

Rosemary Extract Ursolic Acid is the active ingredient of Ursolic Acid extracted from the plant Rosmarinus officinalis, which is rich in antioxidant properties and a variety of biological activities. Green Spring Technology supplies Rosemary Extract Ursolic Acid 98% which is stable in nature, color, and smell do not change with time, and it has a good sense of touch. Widely used as a health food, medicine, and cosmetic raw materials.

Founded in 2000, Green Spring Technology is a leading supplier of plant extracts in China. It has passed many certifications such as Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO, etc. and owns 7 patents. Our products fulfill the highest international industry standards, complying with EU EC396, EU 2023/915 and the highest solvent residue standards. We strictly implement the quality management system and organize production according to ISO, HACCP and other quality standards.

Specification: 

Regulation:

It conforms to EU regulations.

Benefits:

Antibacterial and Antiviral

Tapondjou et al. demonstrated that ursolic acid and hydroxyursolic acid have similar anti-inflammatory and antibacterial effects by acetic acid torsion assay and hot plate method assay. Ursolic acid inhibited the production of formylmethionyl-leucyl-phenylalanine (fMLP) and arachidonic acid-induced superoxide, respectively. Ursolic acid and fMLP were added to cell cultures, and ursolic acid dose-dependently inhibited tyrosine phosphorylation of 45ku protein induced by fMLP. Ursolic acid also possessed trypanocidal activity, and the activity of Trypanosoma cruzi flagellates was completely inhibited after incubation at a concentration of 2 g-L for 2h.

Anti-Atherosclerosis

Rosemary Extract Ursolic acid can reduce blood cholesterol (44%) and B-lipoprotein levels (50%) in rabbits and rats, with hypolipidemic and anti-atherosclerotic effects. Ursolic acid can improve dyslipidemia caused by liver and kidney yin deficiency, tinnitus, dry mouth, less sleep, irritability, numbness and coldness of the limbs, constipation, etc. The total effective rate of lipid efficacy is 95%.

Antioxidant

Rosemary Extract Ursolic acid is a strong antioxidant. Some experiments have shown that ursolic acid can inhibit 5-lipoxygenase and cyclooxygenase activities in the metabolism of arachidonic acid, preventing the production of prostaglandins and leukotrienes, which may be the reason why ursolic acid inhibits inflammation and lipid peroxidation. Subbaramaiah et al. have shown that ursolic acid inhibits transcription of cyclooxygenase in the human mammary epithelial cells, and also inhibits the production of prostaglandins as a result. The antioxidant effect of ursolic acid has a positive effect on human anti-aging, skin blemishes, and pigmentation.

Hepatoprotective and Anti-Inflammatory

Rosemary Extract Ursolic acid is clinically shown to have a significant and rapid reduction of ghrelin, serum aminotransferase, abatement of gangrene, enhancement of appetite, anti-fibrosis and restoration of liver function, with fast effect, short treatment course, and stable effect.

Anti-tumor

Rosemary Extract Ursolic acid also has resistance to a variety of carcinogenic and cancer-promoting agents, and it was found that ursolic acid can significantly inhibit the proliferation of HL-60 cells and induce their apoptosis. It can improve the macrophage phagocytosis function of mice significantly, can inhibit the proliferation of human tongue squamous carcinoma cell line TSCCa cells, the inhibitor amount of the half growth of TSCCa cells is about 12.5 μmol-L-1, and shows a certain quantitative effect relationship within 24h. In situ hybridization showed that the inhibitory effect of ursolic acid on TSCCa cells was related to the inhibition of in situ expression of nuclear transcription factors. In vivo tests proved that ursolic acid could significantly enhance the immune function of the body. This indicates that ursolic acid has a wide range of antitumor effects, and ursolic acid is very likely to become a new type of low-toxicity and effective anticancer drug.

Applications:

In the Food Field:

Rosemary extract has superior antioxidant properties, better than phenolic compounds alone. It affects the permeability of bacterial cell membranes, protein metabolism, and DNA replication, and disrupts bacterial metabolism, thus exerting a certain bacteriostatic effect. Rosemary Extract Ursolic Acid can be used as a natural preservative and antioxidant for food, which helps to extend the shelf life of food and maintain its freshness. It is widely used in food products such as meat products, jams, oil, and fat products to provide protection and stability.

For Feed Product：

Rosemary extract as a new type of green functional feed additive, can effectively enhance the antioxidant and anti-stress ability of animals; improve meat quality; optimize the intestinal flora, reduce the use of VE; promote the growth of animals, improve feed conversion rate, enhance the immune function of the animal, alternative antibiotics.

The addition of rosemary extract to feed improves body weight, feed utilization, meat quality, and antioxidant capacity of chickens. Since rosemary extract contains antibacterial, antifungal, and antioxidant active ingredients, these ingredients can improve the nutrient utilization of poultry diets.

For Health Products:

The addition of rosemary extract to feed improves body weight, feed utilization, meat quality, and antioxidant capacity of chickens. Since rosemary extract contains antibacterial, antifungal, and antioxidant active ingredients, these ingredients can improve the nutrient utilization of poultry diets.